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Buying ammunition
If you have a lot of money, and have unlocked a particular gun, you can buy that gun and sell it for a very reduced price. However, when you sell the gun, whatever ammunition inside it when being sold is be transferred to your inventory, allowing you to "buy" ammo, albeit at a very high price Note: Buy the lowest cost type of gun because the ammunition is universal. For example, it does not matter which pistol to buy, as long as you are trying to get pistol ammunition.

"Caves": Defeating the Boss
When you face the flying bat/insect-like creature for the second time in Chapter 4-1, there is an easy way to defeat him which will allow you to still get the Soul Gem. In the southwest corner of the bottom floor, there is a small pillar of stone in the middle, with what looks to be a log with spikes coming out of it as well as a rib cage hanging from it. When Sheva tells you that it is too hard to fight and you should go upstairs, if done correctly you can just walk backwards without having to dodge around the pillar as the Boss tries to attack you. The "Dodge" button will appear, but it is not necessary. Just continue to walk backwards around the pillar and attack with whatever you have when it is vulnerable, shooting the soft portion on the back of its tail. When it dies you can collect the Soul Gem which is worth 10,000 gold when sold.

"Caves": Easy money
The easiest and quickest way to make money is on Chapter 4-1. Play the level under the Amateur difficulty setting and look for all the treasures. Collecting all the treasures will result in about 40,000 gold. There are seven treasures in part one of the level, ten in part two, and another ten including the Soul Gem worth 10,000 gold in part 3.

"Civilian Checkpoint": Hidden dialogue
Remain idle at the start of Chapter 1-1 before reaching any checkpoints to see a conversation with Chris talking to Sheva about the American dream.

"Experimental Facility": Easy gold
Select the Amateur difficulty for easier kills if desired. Play up until you get to the part where you are in the hallway with all of the Lickers on patrol. Go through it and kill all of them, picking up their Lion Hearts as you go. This is easier when you use a fully upgraded Magnum or rifle because it usually results in one to two shots to kill. When you get to the other end of the corridor, do not open the door. Instead just pause the game and go to quit, saving and overwriting when prompted. When you reach the main menu, go to "Item Management" and sell the Lion Hearts. This usually results in about 12,500 gold each run. Go to "Continue" and restart at the beginning.

"Marshlands": Easy gold and RPG
You can get free treasures worth 11,000 gold and a RPG at the beginning of Chapter 3-1, "Marshlands". There is no need for any use of ammunition or trouble killing zombies. Go to the "Chapter Select" menu. Start Chapter 3-1 "Marshlands". Skip the cinematic if you do not want to waste time. Straight at the first dock, go to the vases. There should be a Ruby (Pear) on the mask (1,000 gold). Go straight to the center of the lake. There should be a Silver Chalice/Idol in the box of the hut (2,000 gold). Go northwest. There should be a half-sunken boat on your way there, with a RPG in the silver box on the deck. Go to the platform at the northwest. Along your way in, there should be a Beetle (Brown) on the fishing fence. At the platform, there should be a Silver Chalice/Idol in the box of the hut. Jump down into the pool. There should be another Beetle (Brown) at left ladder up. (all totaling 4,000 gold). Go up north of map. Go to the end of the village. Help your partner up the left tower to collect the Silver Chalice/Idol in the box (2,000 gold). Note: Do not take the key piece in the box on the left tower, it will trigger enemies to appear. finally, go the southwest village with a long stream leading in. At the village, go straight to the center platform to open the box. You should get another Silver Chalice/Idol (2,000 gold). Note: Do not head elsewhere. Go directly to the box at the center platform. If you go towards to the other huts, it will trigger the zombies to appear. Save and quit the game. Sell the treasures worth 11,000 gold in your inventory. Sell the RPG for another 1,000 gold if you do not wish to keep it. Note: The trick is not to pick up any of the puzzle (key) pieces as this will trigger the enemies to appear. You can break as many vases and pots as desired and collect ammunition and gold bags, but do not pick up the key items. Do not bother to go to the east village to get the other Ruby (Pear), as you might be killed by the Crocs. If everything is done correctly, you will not encounter any enemies but get 11,000 gold worth of treasures and a free RPG.

In addition to the above mentioned information, there are more hidden treasures throughout the area. On the first area with the vases, there is a Brown Beetle on the tree to the left of the key piece. At the area in the center of the lake, there is a Brown Beetle on a post just left of the dock. Also, collect the eggs from the back right corner; they sell for 250 gold each. Also wait to see if any of the chickens lay eggs. On occasion they will lay a golden egg worth 1,000 gold. At the sunken ship to the northwest, there is also a beetle where the ship meets the water. In the area to the very north of the map, there is a ruby on a cow skull on a post near the first hut on the right. In the area following the long stream to the southwest of the map, there is ammunition skewered amongst the posts surrounding it. In addition, there is another beetle on the tree to the right on the way around to the back. If you have trouble finding the beetles, look for purple flowers growing on posts and trees. Also in the north area, there is an Emerald atop the cow skull perched above the sacrificial altar. You must shoot it down. With these additional treasures, it brings the total to between 20,000 to 23,000 gold per run and you will still not encounter any enemies as long as you follow the instructions mentioned in the previous tip.

"Public Assembly": VZ61 machine gun
After the gate has broken open, you can enter the market. Go all the way down the street until you see big red doors and gas cans next to them. Turn right just before the gas cans. There will be a brief case you can open with a VZ61 Machine gun in it. If you look closely, the gun looks similar to the "Scorpion" sub machine gun from Call Of Duty 4. This gun will make this level much easier.

"Shanty Town": Staying together
Go up to the building that has two frag grenades. You can go off of the edge and bounce them off of the sign named "KENNYS". If done correctly, this will blow off the lock, eliminating the need for Sheva and yourself to be separated.

"Ship Deck": Avoid getting trapped
Use this trick to prevent Sheva from getting stuck in the cage in Chapter 6-1. When you go up the first set of stairs on the little walkway, equip a rifle with the scope enhancement (for better zoom capabilities). Look up at the crane. You will see a Manjini getting ready to pull the lever to trap Sheva in the cage and setting off the ambush. Kill it the prevent the ambush. However, if you do this trick you will not be able to access the crane area without the keycard, and thus not able to move the cage to access a gold bar worth 3,000 gold across a few containers in a safe.

"Storage Facility": Easy gold
Start Chapter 2-1 under any difficulty setting with a friend via the Internet. Note: You must have eggs to do this trick. Begin your game with your partner. Have whoever has the eggs drops out of the game, leaving all the eggs to the AI character. Have the other person then request all of the eggs from the AI character and complete the level, making sure that the game saves. Then, go back into the game with your partner at the same level, making sure that you have the eggs in every inventory slot. Then, drop out, leaving all the eggs to the AI. Have your partner request all the eggs, then complete the level. You can repeat this as many times as desired. The eggs will multiply each time you do this and you can sell them for 2,000 gold. This is a way to receive unlimited amounts of money to buy whatever you need.

"Storage Facility": Skip locked gate
You will go up a building before fighting the chainsaw enemy at the end of Chapter 2-1. At the top you usually have to split up and have Sheva go to the other side of the locked door down below. Use the following trick to skip this requirement. Get the grenade from the first balcony up the stairs in the building with the locked door. Go to the very first balcony of the building, and move directly across from the "Animal Health" sign. Throw the grenade at the sign, aiming slightly lower than needed. You need to bounce the grenade off the sign to have it land next to the locked door which is below it. If done correctly, this will destroy the lock. You can now simply go downstairs and exit through the now open door. Note: If you have the Gatling gun, simply push it through the door and it will shoot off the lock from the other side.

"Train Station": Easy money
In section 2-2 in the mining area, after the cinematic where the masked person takes the man in the suit away, you will have a great opportunity for easy treasure. Immediately in the area that follows is a brilliant diamond worth 4,000 gold and smaller diamond worth 2,000 gold. While you are upstairs, next to the windows will be a locker that you can open. Inside is a sniper rifle in case you need it. Downstairs are two enemies that you should get rid of to make things easier. Then from upstairs, you can pick off the half-dozen or so enemies that are waiting for you outside with the sniper rifle. After you take care of all or most of them, run out. To your left behind all the equipment is a small red ladder. Climb it, and to side farthest from you will be a chest. Inside will be the big brilliant diamond. Go back and walk past the truck with the turret. Look up towards the end of the first long red ladder. You will see a shining spot. Shoot it, and the smaller diamond will drop for you to pick up. In about five minutes or less you will make an easy 6,000 gold. Quit the game and select "Yes" when prompted. This will save your equipment and treasures. Reload, continue the game, and repeat the process. You will soon accumulate enough money to upgrade your weapons. To make even more money, only equip the new sniper and keep picking it up or giving it to Sheva. Also keep selling it to get extra money.

"Train Station": Hidden Majini
In the third part of the level, find the green portable toilet past the truck with a Gatling gun. Knock on it to find a hidden Majini.

"Uroboros Research Facility": Easy ammunition
In Chapter 5-2, "Uroboros Research Facility", after the conveyor belt area and you start a new checkpoint, you reach a point where you drop down. There are a number of crates with flame rounds, rifle rounds, handgun ammo, and an incendiary grenade. Collect everything, then save the game and quit. When you start again, remove the collected items from the item management screen and collect them all again. You can get 300 handgun bullets in a matter of ten minutes.

B.S.A.A. emblems
Shoot the thirty hidden B.S.A.A. emblems to unlock items at the "Bonus Features" menu. Note: When replaying a level to find emblems, there is no need to continue to a checkpoint. The game will record it as collected as soon as it is shot.

Chapter 1-2
Find the building with a staircase leading up to a locked door. There are two shade umbrellas here. Stand near top of the stairs and look past the wall facing southeast to the emblem on the wall high on the building opposite.
Kill the blond woman and enter the next area. Navigate the dark area and go up the stairs. Enter the room with no roof. Look up at the water tower just before the cinematic with the dead soldiers.
Defeat the furnace Boss then go through door that requires the furnace key. Look through the fence to the left of the ammunition case.

Chapter 2-1
On the wall above you at the starting room.
Cross the bridge, then look at one of the bridge supports just before entering the tunnel.
Enter the town after the tunnels and go to the water's edge. At the small beach before you return to the market, look at the large boat and the green shack. The emblem is in the roof on its side.
At the shop with the green and white canopy and the word "Stores" on it, the emblem is between one of the arches. It can been best seen from the rooftop, just as you get helicopter support.
Climb up to the top of the building and get Sheva to jump across to the other building so she can unlock the door. Turn around and look up.

Chapter 2-2
Exit the building at the start. Look towards the top of the pylon. You can climb on one of the carriages for a better view.
Inside the mine as you cross the first bridge, look to your right, high on the rocks.
Exit the mine and go outside. After the cinematic with Irvine, go outside. Move past the mounted gun and climb the larger of the two ladders at the end. Turn to the left to see the emblem on the building in the distance.

Chapter 3-1
Use a sniper rifle to aim at the mid-section of the telephone pole to the north of your starting position.
When free roaming with the hovercraft, travel to the northwestern tip of the map. Get out and look on the roof of the hut.
From where you collected the slate map to the west, stand on the edge of the wooden walkway. Use a sniper rifle to zoom into the central island to the east to find the emblem on the hut wall.
Insert all the pieces to open the door. Drop down into the water and face south to find the emblem on the wood.

Chapter 3-2
Escape the walkways and enter the area with Tricell tents. Move behind the tents and look between them.
Look at the shack on your left as soon as the timer starts on the docks.

Chapter 3-3
Exit the boat for the first time, then look east at the entrance you just used. The emblem is barely visible.

Chapter 4-1
Climb up to the first ladder then turn to the right. Look down below on the rock face to the right of waterfall.
After the cinematic with the panoramic view of the ruins ends, use a sniper rifle to zoom in at the base of the reflective object in the distance.
Complete QTE from the falling statues and pull the two switches. Take the left path when you enter the labyrinth. Follow it until finding a square archway. Look to your left before passing through the archway. Look above the green statue to find the emblem near a tree on the wall.

Chapter 4-2
Make your way down to the second elevator and enter the room with the statue near the entrance. The emblem is above the entrance.

Chapter 5-1
Move around the raised area counter-clockwise when the mission starts. The path will be blocked but the emblem can be seen under the metal bridge.

Chapter 5-2
Proceed through the level until after you exit the conveyor belt with the gas canisters. You will find a gun case and two dumpsters on the left wall. Look inside the open dumpster. Note: It is found before you pull the switch for the conveyor that needs to be powered.

Chapter 5-3
You will see two large fans after you exit the Boss room. Look behind the fan on the right.
Reach the circular moving platform. Move to the bottom of steps then turn east. Look towards the platform above you in the distance to see the emblem through the floor with a sniper rifle.
Enter the area with the ruins and go to the small elevator on the left. Walk around it to where the rifle ammunition is hidden. Look into the elevator shaft to find the emblem.

Chapter 6-1
Turn 180 degrees when the mission stars. Look at the very top of the radar's silhouette with a sniper rifle.
Face northwest when Sheva is trapped in cage and fire a grenade into the container.
Search the glass cabinet on the left next to plant's displays.

Chris' S.T.A.R.S costume
Collect 25 B.S.A.A. emblems.

Completion bonuses
Successfully complete the game under any difficulty setting to unlock the following bonuses:

"History Of Resident Evil" option
"Infinity ammunition" option (must fully upgrade a weapon then purchase the unlimited ammo from the "Bonus Features" section with points)
Chris' Safari and Sheva's Clubbin' alternate costumes
Mercenaries mode
New Game+ mode
Play as Sheva Alomar

Successfully complete the game under five hours (get an "S" rank) under any difficulty setting to unlock the Infinity Rocket Launcher.

Successfully complete the game under the Amateur difficulty setting to unlock the "Classic Horror Filter" option.

Successfully complete the game under the Normal difficulty setting to unlock the "Retro Filter" option.

Successfully complete the game under the Veteran difficulty setting to unlock the following bonuses:

"Noise Filter" option
Professional difficulty

Costumes
Complete the indicated task to unlock the costume for campaign:
Costume How to unlock
Clubbin' Sheva
Beat the game

S.T.A.R.S. Chris
Shoot 25 BSAA emblems

Safari Chris
Beat the game

Tribal Sheva
Shoot 30 BSAA emblems

Defeating Lickers
The Lickers are far more difficult than in previous Resident Evil games. However, they have a weakness. Notice they have a "heart" hanging down from their chest. The best way to target this is to use a rifle (for example, the PSG-1). Target the darker red bulge. If you cannot get a clear shot at it, score a head shot and they will recoil, making the chest more vulnerable and easier to target. With the PSG-1, this will allow for a two shot kill, or perhaps a one shot kill if you can hit the heart with the first shot. Hand grenades also work very well.Tthey will completely disappear when hit with a grenade. This is very useful in Chapter 5-3 when you have to face a large number of them.

Defeating Wesker
To quickly and safely defeat Wesker in his first form, run to all the levers around the map to turn the lights off. You do not need to go up the ladders because there are no levers up there. Do not worry about attacking him until you have turned off all the lights, otherwise you will not be able to hit him. After all the lights have been turned off, take the rocket launcher in the display case after breaking it open. Run to a dark corner far away from him. Wesker will look around to try and find you. When this happens, you will have a chance to shoot a rocket at him. As soon as you shoot it, he will grab it. Run up to him (or shoot the rocket in his hands), stun him, and initiate a button context. If you need more ammunition you can send Sheva to fetch it, or you can get it by climbing to the area above the ladders. The second form is nothing but a button context scene battle, and there is no specific strategy needed. In his final form, start by running to the high ground. Then when in the circular area, shoot the orange "heart" that alternates from his chest to his back while dodging his attacks. After he takes enough damage, he will go after Sheva. At this point, run down the ramp from the circular area you were just in. Make a left to arrive at a large boulder. Instead of interacting with the boulder just yet, shoot Wesker from afar, while Sheva hangs in the balance. Once she lifts herself up, start to move the boulder using the button contexts. Make your way back to the high ground and repeat the orange heart strategy until he has been defeated.

Use the following trick to defeating Wesker's Final Form. Once you have saved Sheva from Wesker and have pushed the boulder over to allow her to join you, you will once again be attacked by Wesker, when you run to the higher ground where you faced him earlier. Like before, dodge his attacks as you shoot his heart, which alternates between his chest and back. Once you do enough damage to his heart, he will kneel down and push his arm into the ground. It then comes up around him as many swirling tentacles, protecting him from fire. If you wait and do nothing after he gets back up, you will see a cinematic of tentacles recovering his heart, which you do not want to happen. To prevent this, as soon after the swirling tentacles recede, run up to him and there should be a button event will begin, allowing you to hold him while Sheva stabs him (and later you), which is how you can finally kill him.

Devil May Cry 2 reference
The name for the virus in Resident Evil 5, Uroboros, is also used as a name for the corporation in Devil May Cry 2, another Capcom game.

Dodging
Picking up an item allows you to dodge an attack. This works best when surrounded by enemies. Stand above an item on the floor while shooting. If you miss someone who runs up to you, just pick up the item. Your character will duck the attack and the enemy will be open for a counter-attack. Kill him, stand over the item that he drops, and continue.

Easy "Bad Blood" achievement or trophy
This is unlocked by issuing a set amount of damage towards Wesker before the seven minute deadline during your first encounter in the Monarch Room. An extremely easy way to do this is to use an RPG. Just as the fight starts, run to a blue metal door on the right of the map. Check the door and it will say that it is locked. After you are done checking out the door, a cinematic will start, where Wesker kicks Chris through the door. Immediately after this cinematic, run to the left up the stairs and then to the end of the corridor. Go up against the wall and lean out with your RPG in hand. Just when Wesker comes up the stairs, shoot a rocket at him. He will catch it, then struggle for a few seconds. Shoot another rocket as soon as you can when you see this happening. Both will explode in his face. He will run directly up to you, but not attack. Instead, he will spin and twirl away. Your battle with Wesker will be over and you will have one more achievement or trophy. Do not forget to pick up the Heart of Africa treasure (worth 10,000 gold) during your fight will Jill because of this. It is located between two staircases in the main room.

Easy "Bull's-Eye" and "Crowd Control" achievement or trophies
After unlocking and purchasing Chris' chain-gun (fully upgrade the VZ61) and Sheva's bow (fully upgrade the S75), play the first level and get past your first encounter with the Majini. After jumping out the window you will come to a back alley where you are ambushed by a group of Majini. Kill all the Majini, and not only will you get whichever achievement or trophy you are attempting to unlock, but at the end of the horde you can pick up the Topaz (Marquise) worth 3,000 gold.

Easy "Egg Hunt" achievement or trophy
If you have a friend who has all four eggs, they can give them to you at the inventory screen. Just remove them from your active inventory and you will get the achievement or trophy.

Find three of the four eggs on Chapter 4-1 in the middle island with all the chickens. The rotten egg is randomly dropped by Majini is Chapters 6-1 through 6-3.

Easy "Egg On Your Face" achievement or trophy
Once you acquired a rotten egg, go to either Chapter 1-1 or 1-2 and play under the Amateur difficulty setting to ensure a one hit kill. Equip the egg and headshot any Majini. If you miss, quit the game but do not save. By doing this, you will still have the egg.

Easy "Go Into The Light" achievement or trophy
Go to Chapter 4-1, "Caves", and pick up the flash grenade from the pots at the start of the level. Run forward until you trigger the Bui kichwa (spider enemies). Use the flash grenade against the first swarm and it should kill them all in one hit.

Easy "Masters Of Removing" achievement or trophy
This trick requires a friend and lots of flash grenades. The rocket launcher is also recommended because Jill moves around a lot. When the fight begins, Jill will jump down from the balcony. Just as she lands, hit the ground near her with a flash grenade. Try to avoid hitting Jill directly because a flash grenade can kill her. She will be temporarily blinded, allowing your teammate to restrain her from behind. Run up to Jill and shoot the control device, but do not attempt to pull it off just yet. Depending on the difficulty setting, do this four to six times then attempt to pull the device off. Use a high powered single shot gun when shooting the control devicem like the PSG-1 or any Magnum, because it will help speed up the process.

Easy "S" ranks in Campaign mode
Use the RPG with infinite ammo enabled, then just rush through the level. Kill every enemy you encounter. Because you are using the RPG, enemies are killed easily from direct hits and splash damage. Your accuracy will be rather high. Because you are killing all the enemies your kill count will be high. Because you are rushing through the level your clear time will be low. This is especially useful when trying to unlock the final figure of Wesker for the "They're ACTION Figures!" achievement or trophy.

Easy "The Works" achievement or trophy
Note: You must go into this prepared. If playing in Single Player mode, ensure that Sheva has no weapons. By doing this, she will not shoot when you do not want her to. You will also need a flash grenade. If you do not have one, go to Chapter 4-1 and get it at the start. Quit the level and save your equipment. Go to Chapter 6-1, "Ship Deck". Kill all the enemies that are triggered when you drop down. Continue past the tower and drop down near the containers. Go to the stairs to the right, which will trigger a few Adjule (dogs). Dispose of them quickly, because there are two Majini with melee batons coming down the stairs. Once these enemies are disposed of, continue forward until you hear a Big Man Majini yell at you. Immediately pull back so you do not trigger any other enemies. Lure the big Man Majini to where you just fought the Adjule. Use your flash grenade to stun him, then run up to him and use the contextual action to do a melee attack, Sheva will do another attack which you will follow up immediately with another contextual action attack. This will dispose of the Big Man Majini and grant you the achievement or trophy.

Easy "Who Do You Trust?" achievement or trophy
After you unlock infinite ammunition with the RPG, go to any level. Run up to any wall and shoot at it close-blank range with the RPG. This should bring you into "dying status", and Sheva will try to o revive you. Tap Circle just when she does and Chris will say something similar to "Thanks" or "Thanks for the help". Continue to do this to thank Sheva and you will unlock the achievement or trophy in about five minutes as opposed to having to play through the entire game.

Easy money
This trick will help you gain money to max out and buy all the weapons. In any chapter, collect as much gold, items, ammunition, and treasure you can find. When you are satisfied, pause game play and quit the game. Save the game when prompted. Restart any desired chapter. The "Shop" menu will appear before the start of any chapter. Notice that all the gold, treasure, weapons, and ammunition from your previous saved game are still in your inventory. From there, you can sell anything you want to gain some fast cash. This glitch can be done repeatedly, on any chapter.

Go through a chapter, collecting as many hand grenades as possible. Then, start Co-op mode with a friend, system link, or over the Internet. Give your partner all of your grenades and have them exit the game. After they leave, your AI partner will still have all of the grenades. Make sure you request them back. While you do this, your friend that left can sell the ones he took with him. You can have up to five in each slot, and they sell for 250 gold each. You will gain 11,322 gold each time you do this (if you have all your slots full). This is also a good way to stock up on ammunition.

Start Chapter 2-1 under any difficulty setting with a friend via the Internet. Note: You must have eggs to do this trick. Begin your game with your partner. Have whoever has the eggs drops out of the game, leaving all the eggs to the AI character. Have the other person then request all of the eggs from the AI character and complete the level, making sure that the game saves. Then, go back into the game with your partner at the same level, making sure that you have the eggs in every inventory slot. Then, drop out, leaving all the eggs to the AI. Have your partner request all the eggs, then complete the level. You can repeat this as many times as desired. The eggs will multiply each time you do this and you can sell them for 2,000 gold. This is a way to receive unlimited amounts of money to buy whatever you need.

As soon as you defeat the Uruoburos for the second time you can repeat the beginning of that chapter and collect lots of money and ammunition (especially for the machine gun). Repeat this several times and you will be able to upgrade every weapon in your arsenal.

Easy quick game
Use the following trick to get a combined clear time for the entire game of under five hours (to unlock unlimited RPG ammunition). A really easy way of doing this is to play under the Amateur difficulty setting and just run pass all enemies. Only kill story-driven enemies (ones that hold key cards or those that must be defeated to advance the game). Also, avoid any crates, barrels, or treasures. Attempting this with a friend instead of the CPU-controlled Sheva is recommended. Note: You do not need to purchase the infinite ammo in "Bonus Features" as you would do for normal guns.

Efficient healing
If both players stand in front each other and one of them heals themselves, both persons will get healed.

Lure away move
Press L3 + R3 to do a "lure away move", where Chris will say "Come on, come on!" or Sheva will whistle. This actually lures away regular enemies towards you just in case your partner is low on health, trying to pull something off, crank something, etc.

Mercenaries mode: Characters
Earn an "A" or higher rank in the indicated Mercenaries mode mission to unlock the corresponding character.

Chris (Safari): "The Village" mission
Chris (S.T.A.R.S.): "Experimental Facility" mission
Jill (Battle Suit): "Ship Deck" mission
Jill (B.S.A.A.): "Public Assembly" mission
Sheva (Clubin): "Ancient Ruins" mission
Sheva (Tribal): "Missile Area" mission
Wesker (Midnight): "The Mines" mission
Wesker (S.T.A.R.S.): "The Prison" mission

Mercenaries mode: Easy completion
Have two players so that one can rack up kills. Have one of the players immediately go for the time bonuses instead of getting too caught up with enemies. Get about five minutes worth of time. If you can, collect the combo time to rack up some serious points. Then, meet up with your partner and find a good place to hold out and accumulate points. Every level plays out differently and can be more difficult than others with this strategy. Try making a route for each time bonus. Note: If you are playing on "Public Assembly" or "Ship Deck" do not find a hiding location. Instead, move and kill or the chainswaw Manjinis or executioner will catch up to you and kill you.

Mercenaries mode: Getting better ammunition
The ammunition that drops is based on the type of weapons you have. Drop weapons that you will not use to increase the chance of getting ammunition that is more useful.

Mercenaries mode: Quick reload
Display the inventory screen and combine ammunition manually with your weapon. This causes weapons such as the shotgun to reload much faster than the normal method. You can also use this trick while climbing ladders or jumping.

Reload your weapon when the melee option appears. Then, start the melee sequence. Your weapon will be reloaded instantly.

Mercenaries mode: Wesker's Dash move
While playing as Wesker in Mercenaries mode, click the R3 to dash. You can press Square during a dash to do a knee attack.

More Trophies
The following trophies require the bonus downloadable content.
Trophy How to unlock
Army of One ( Bronze )
Win 30 matches in Slayers.

Bringing the Pain ( Silver )
Defeat 100 players using physical attacks in Versus.

Eye of the Tiger ( Bronze )
Win 30 matches in Survivors.

It Takes Two to Tango ( Bronze )
Chain a 40-defeated combo in Team Slayers.

It's All About the Points ( Bronze )
Score at least 40,000 points in Survivors.

Keep the Good Times Rolling ( Bronze )
Chain a 20-defeated combo in Slayers.

Let's Get This Party Started! ( Bronze )
Unlock all selectable characters in Versus.

The Team That Slays Together... ( Silver )
Win 30 matches in Team Slayers.

There's no "I" in Team ( Bronze )
Score at least 80,000 points in Team Survivors.

We Will Survive ( Silver )
Win 30 matches in Team Survivors.

Obtaining the Heart Of Africa
To get the Heart Of Africa treasure you must do a set number of damage to Wesker during the first fight with him and Jill. The best way is to have the Infinite Magnum. You will also get the achievement if it is your first time. After you defeat him and start of the Jill fight, the treasure will be between the two curved staircases. Also, do not forget to get the gem in the southeast corner of the room you enter in the crate, and the two in the tombstone upstairs, and the one nearby in the little pot.

Public Assembly: VZ61 machine gun
After the gate has broken open, you can enter the market. Go all the way down the street until you see big red doors and gas cans next to them. Turn right just before the gas cans. There will be a brief case you can open with a VZ61 Machine gun in it. If you look closely, the gun looks similar to the "Scorpion" sub machine gun from Call Of Duty 4. This gun will make this level much easier.

Regenerate items
Chapter 2-1, take all the items at the beginning and then Quit the game. Return to the game by selecting "Continue" and you will begin Chapter 2-1 with the items you got before you quit the game, however, the items at the beginning (you took just now) are still at the same place, so you can obtain them again. Repeat the same thing to get as many as you like.

Note: This works on any stage, this is just one example of how to benefit from it.

Rocket Launcher
To unlock the Rocket Launcher with infinite ammo, beat the game under 5 hours on any difficulty, and turn infinite ammo on under bonus features.

Shanty Town: Staying together
Go up to the building that has two frag grenades. You can go off of the edge and bounce them off of the sign named "KENNYS". If done correctly, this will blow off the lock, eliminating the need for Sheva and yourself to be separated.

Sheva's Tribal costume
Collect 30 B.S.A.A. emblems.

Treasure
Search the listed locations to find the indicated treasure pieces.

Antique Clock
Chapter 1-2: On the balcony of the house that is locked from the inside.

Beetle (Brown)
Chapter 3-1: On the small island where you start.
Also found elsewhere in multiple locations in Chapter 3-1.

Beetle (Gold)
Chapter 4-2: On the bottom floor of the mirror puzzles, in one of the room that unlocks send the beam of light to the statue instead of the final mirror.

Beetle (Jewel)
Chapter 3-2: On top of the oil drums at the Tricell camp.

Blue Enigma
Chapter 3-1: Kill a giant Manjini.

Ceremonial Mask
Chapter 3-1: In an alcove to the right of the gondola at the end of the chapter.

Chalice (Silver)
Chapter 3-1: On the middle island (the chicken farm).
Also found elsewhere in multiple locations.

Chalice (Gold)
Chapter 5-3: When in the room with the drawbridge and swarm of Lickers, look in a locker after you drop down into the locked room.

Dead Bride's Necklace
Chapter 5-2: Lying near the discarded corpses on the conveyor belt.
Chapter 6-1: Dropped by the rocket launcher wielding Majini.

Diamond (Brilliant)
Chapter 2-2: After the scene with Irving, go downstairs and outside. Walk towards the machine gun turret and look for a small ladder on your left. The gem is in a chest on that ledge.

Diamond (Marquis)

Note: You must be playing as Chris if in Solo mode. During the final fight with Wesker at the volcano, immediately after Wesker appears for the first time, turn around and move towards the bridge that will collapse. Before stepping on it, shoot down the rock just past it that is the same color. When you fall through the bridge, turn to your left then jump over the rock to collect the gem.

Diamond (Oval)

Chapter 2-2: In the mines just before the crank at the exit, turn left off the cart tracks. Follow the wall to a chest containing the gem.

Diamond (Pear)
Chapter 2-2: After the scene with Irving, go past the machine gun turret. Aim at the top of the large ladder to shoot it down.

Diamond (Square)
Chapter 2-2: After the scene with Irving go past one more checkpoint. There is a broken ladder with an assist jump here. The gem is on the ledge Sheva lands on. Follow her around to where she climbs, then jump down one level to get it.

Diamond (Trilliant)
Chapter 4-2: After putting in all three emblems in the door, go up the stairs. Shoot the gem down from above the big door you have to enter.

Emerald (Brilliant)
Chapter 5-3: At the start of the Wesker and Jill fight at the end of the chapter, run up the staircase on the right in front of you. Follow the path round to the right. The gem is in one of the pots at the end.

Emerald (Marquis)
Chapter 3-3: After leaving the boat for a second time, climb a ladder to the ledge with the two machine gun turrets above the gate you are trying to open. The gem is in a drawer in the room between the guns.

Emerald (Oval)
Chapter 5-3: Turn around after Wesker kicks you through the door. Follow the corridor into a room with the coffins. The gem is in a coffin that needs an assist event to open.

Emerald (Pear)
Found in multiple locations.

Emerald (Square)
Found in multiple locations.

Emerald (Trilliant)
Chapter 4-1: After you fall down from the trap with the empty sarcophagus, the gem is in one of the three treasure chests.

Gold Ring
Chapter 1-1: Kill the Executioner at the end of the chapter.
Also found elsewhere in multiple locations.

Heart Of Africa
Chapter 5-3: Between the stairs during the Jill solo fight after you ended the previous fight by damaging Wesker enough to make him retreat.

Idol (Silver)
Chapter 3-1: On top of the left of the two assist jumps on the northeast island.

Idol (Gold)
Chapter 4-2: On the bottom floor of the mirror puzzles, in one of the room that unlocks send the beam of light to the statue instead of the final mirror.

Ivory Relief
Chapter 1-2: Dropped by the blonde woman you help.

Jewel Bangle:
Dropped by a "Big Man" Manjini.

Lion Heart
Kill a group Lickers until one drops.

Power Stone
Kill a Reaper.

Royal Necklace
Chapter 5-3: Inside the control room being guarded by a group of rocket launcher wielding Manjini.

Ruby (Brilliant)

Chapter 5-3: Leave the room with the giant rotating elevator. Look at the ceiling between the last two lights as you emerge from the tunnel in the next room.

Ruby (Marquis)

Chapter 2-1: - During the fight in the market area where you have to shoot a key from a hanging dead body, toss a grenade into the middle stall with a chest in it. The gem is in that chest.

Ruby (Oval)
Chapter 4-1: Behind the red statue in the labyrinth.

Ruby (Pear)
Found in multiple locations.

Ruby (Square)
Found in multiple locations.

Ruby (Trilliant)
Chapter 4-1: After you fall down from the trap with the empty sarcophagus, the gem is in one of the three treasure chests.

Sapphire (Brilliant)
Chapter 5-3: Turn around after Wesker kicks you through the door. Follow the corridor into a room with the coffins. The gem is in a coffin that needs an assist event to open.

Sapphire (Marquis)
Chapter 5-3: At the beginning of the level, leave the Boss room. Follow the path around and take a left at the fork. The gem is in a safe to your left as you enter the room.

Sapphire (Oval):

Chapter 5-3: Turn around after Wesker kicks you through the door. Follow the corridor into a room with the coffins. The gem is in a small pot on the shelf to the right as you enter.

Sapphire (Pear)
Found in multiple locations.

Sapphire (Square)
Found in multiple locations.

Sapphire (Trilliant)
Chapter 4-1: After you fall down from the trap with the empty sarcophagus, the gem is in one of the three treasure chests.

Soul Gem
Chapter 4-1: Kill the Boss at the end of the level without using the reaction event (before climbing the stairs to the exit).

Topaz (Brilliant)
Chapter 5-3: In the room with the drawbridge and the swarm of Lickers, the gem is high on the wall in front of you as you cross the drawbridge.

Topaz (Marquis)
Chapter 1-1: After you jump out of the window, take out all the Majini and one of them will drop it.

Topaz (Oval)

Chapter 6-1: Under the Normal, Veteran, or Professional difficulty, go up the ladder just before the assist push. Turn around and find a person that you will have to fight later. Shoot him now. Go through the gate scene and on your way to the crank, turn right after the stairs.

Topaz (Pear)
Found in multiple locations.

Topaz (Square)
Found in multiple locations.

Topaz (Trilliant)

Chapter 4-1: At the beginning, before you climb up the first ladder go straight towards the end. The gem is in the treasure box.

Venom Fang
Kill a chainsaw Manjini. Note: The first one encountered will not drop one.

Trophies
Complete the following tasks to unlock PlayStation 3 trophy rewards.
Trophy How to unlock
A Cut Above (Bronze)
Defeat 5 enemies with the Knife.

A Friend in Need (Bronze)
Save partner 10 times when HELP is displayed.

All Dressed Up (Silver)
Purchase all available alternative costumes in Bonus Features.

Bad Blood (Bronze)
During the first fight with Wesker, damage him a set number of times.

Badge of Honor (Silver)
Find all the BSAA emblems.

Baptism by Fire (Bronze)
Defeat 3 Majini at once with a drum or gas tank explosion.

Be the Knife (Silver)
Deflect a bow gun arrow with your knife.

Bull's-eye (Bronze)
Defeat 30 enemies with the Longbow.

Cattle Prod (Bronze)
Defeat 30 enemies with the Stun rod.

Crowd Control (Bronze)
Defeat 30 enemies with the Gatling gun.

Completed Chapter 1 - 1 (Bronze)
Complete Chapter 1 - 1 on any difficulty setting.

Completed Chapter 1 - 2 (Bronze)
Complete Chapter 1 - 2 on any difficulty setting.

Completed Chapter 2 - 1 (Bronze)
Complete Chapter 2 - 1 on any difficulty setting.

Completed Chapter 2 - 2 (Bronze)
Complete Chapter 2 - 2 on any difficulty setting.

Completed Chapter 2 - 3 (Bronze)
Complete Chapter 2 - 3 on any difficulty setting.

Completed Chapter 3 - 1 (Bronze)
Complete Chapter 3 - 1 on any difficulty setting.

Completed Chapter 3 - 2 (Bronze)
Complete Chapter 3 - 2 on any difficulty setting.

Completed Chapter 3 - 3 (Bronze)
Complete Chapter 3 - 3 on any difficulty setting.

Completed Chapter 4 - 1 (Bronze)
Complete Chapter 4 - 1 on any difficulty setting.

Completed Chapter 4 - 2 (Bronze)
Complete Chapter 4 - 2 on any difficulty setting.

Completed Chapter 5 - 1 (Bronze)
Complete Chapter 5 - 1 on any difficulty setting.

Completed Chapter 5 - 2 (Bronze)
Complete Chapter 5 - 2 on any difficulty setting.

Completed Chapter 5 - 3 (Bronze)
Complete Chapter 5 - 3 on any difficulty setting.

Completed Chapter 6 - 1 (Bronze)
Complete Chapter 6 - 1 on any difficulty setting.

Completed Chapter 6 - 2 (Bronze)
Complete Chapter 6 - 2 on any difficulty setting.

Completed Chapter 6 - 3 (Bronze)
Complete Chapter 6 - 3 on any difficulty setting.

Drive By (Silver)
Stop an armored truck by taking out the driver.

Egg Hunt (Bronze)
Find all 4 types of eggs.

Egg on Your Face (Bronze)
Defeat a Majini with a rotten egg.

Exploding Heads (Bronze)
Pull off 20 headshots.

Fireworks (Bronze)
Shoot an enemy Molotov cocktail, dynamite stick, or hand grenade.

Get Physical (Bronze)
Defeat 20 enemies with physical attacks.

Go into the Light (Bronze)
Defeat 2 enemies with one flash grenade.

Heart Stopper (Bronze)
Defeat a certain enemy by stabbing it in the heart.

Lifeguard (Bronze)
Save partner 10 times when DYING is displayed.

Lead Aspirin (Silver)
Defeat a Majini with a headshot while it's jumping.

Meat Shower (Bronze)
Defeat 3 Majini with one grenade or proximity bomb.

Masters of Removing (Bronze)
Work together to save someone special.

Recruit (Bronze)
Complete all chapters on Amateur.

Resident Evil 5 Platinum Trophy (Platinum)
Congratulations! You've overcome all your fears in Resident Evil 5.

Ride the Lightning (Bronze)
Defeat a Majini using the electric current from a transformer.

Stop, Drop, & Roll (Bronze)
Defeat 3 Majini at once by setting oil canisters on fire.

Soldier (Bronze)
Complete all chapters on Normal.

Stockpile (Silver)
Obtain all available weapons.

Take It to the Max (Silver)
Completely upgrade all weapons.

They Belong in a Museum (Silver)
Obtain all treasures in the game.

They're ACTION Figures! (Silver)
Collect all the figurines.

The Works (Bronze)
Chain the maximum number of combos together in one go.

Veteran (Silver)
Complete all chapters on Veteran.

Who Do You Trust? (Silver)
Build up a certain level of trust with your partner.

War Hero (Bronze)
Complete all chapters on Professional.

Unlimited money
At the beginning of Chapter 2-1, you will be in a garage with two Humvees, numerous breakable crates, and a machine gun. Pick up any items you wish, including the machine gun. End the game, and select "Yes" to overwrite your current equipment. Continue the game from the main menu. You will have gained your items, as well as the machine gun. From here you can sell the machine gun back for quick money, then repeat the process over again. This is an easy way to help upgrade your weapons early, as well as max your ammo out.

Find a rotten egg in Co-op mode. It is worth 2,000 gold. One player will be acting as a "bank". Before every level, go into an inventory screen to organize it. Both players must have their inventory empty, but the player with the egg needs to keep it in his or her inventory. Start the game and it will save automatically when the level loads. After it saves, have the player with the rotten egg give it to their partner. You will be asked if you want to overwrite your inventory. The player that gave the egg must choose "No", and the player that is now holding the egg mush choose "Yes". The player that is giving the egg will still have it in his or her inventory, and the other player will now have one. Continue this process and the egg count will continue to double until your inventory is full with 45 eggs. At this point you can place them in your storage box and continue this glitch until you have the desired amount of money.

Unlockable Home items
Complete the following tasks to unlock Resident Evil 5 items in Home.

Unlockable How to Unlock
Chris Redfield Ornament
Sign in to Home and you will automatically get it

Jill Valentine Ornament
Beat the game on veteran

Sheva Alomar Ornament
Beat the game on normal

Treasure Chest Ornament
Collect all treasures in the game

Versus Mode: Unlockable Characters
These are the 8 unlockable characters for the DLC Versus Mode. While the same as Merceneries, they only have slightly different weapon-sets.
Character How to unlock
Chris(S.T.A.R.S)
Unlock him through the Bonus Features menu at the cost of 13,000 Exchange Points

Chris(Safari)
Unlock him through the Bonus Features menu at the cost of 8,000 Exchange Points

Jill(Battle Suit)
Unlock her through the Bonus Features menu at the cost of 5,000 Exchange Points

Jill(BSAA)
Unlock her through the Bonus Features menu at the cost of 5,000 Exchange Points

Sheva(Clubbin')
Unlock her through the Bonus Features menu at the cost of 6,000 Exchange Points

Sheva(Tribal)
Unlock her through the Bonus Features menu at the cost of 15,000 Exchange Points

Wesker(Midnight)
Unlock him through the Bonus Features menu at the cost of 5,000 Exchange Points

Wesker(S.T.A.R.S)
Unlock him through the Bonus Features menu at the cost of 5,000 Exchange Points

Weapon upgrades
Upgrade the indicated weapon fully to unlock the corresponding bonus weapon for purchase from the shop.

Gatling gun for Chris: Fully upgrade the VZ61.
Hydra triple barrel shotgun: Fully upgrade the Ithaca M37.
Longbow for Sheva: Fully upgrade the S75.
M93R pistol (Samurai Edge Custom): Fully upgrade the M92F.
Smith and Wesson M500 Magnum (Handcannon): Fully upgrade the Smith and Wesson M29 Magnum.